Search Results - bio-tech

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Real Time Immunoassay Detection on a Chip

This chip based system incorporates microfluidics with label free optical detection. It can be used to replace ELISA based detection schemes for point of care detection of infectious diseases, cancer, and other diseases detected using antibodies or alternative chemical recognition means. The technology has been demonstrated in Dengue fever detection...

Published: 10/17/2017 | Updated: 11/12/2013 | Inventor(s): Pierre Berini

Keywords(s):

Category(s): Bio-Tech, Chemistry, Engineering, Life Sciences

Inhibitors of Nucleophilic Enzymes for therapeutic and drug discovery applications

These inhibitors are based on hydrazone derivatives produced using a novel synthetic route. The compounds react with the active site of nucleophilic enzyme, which typically have a nucleophile such as an amine, alcohol, or thiol on the side chain (for example - lysine, serine, and cysteine). In reacting at this site, the enzyme is inhibited. Such inhibition...

Published: 11/18/2015 | Updated: 7/19/2013 | Inventor(s): Andre Beauchemin, Keira Garland, Alison Sherratt, John Pezacki

Keywords(s):

Category(s): Bio-Tech, Chemistry, Life Sciences

Efficient synthesis of synthetic peptides containing beta-aminocarbonyls

Beta-aminocarbonyls are found in several major drugs and are increasingly important in synthetic peptides. This method reduces the cost of synthesizing beta-aminocarbonyl structures by reducing the number of steps in the synthesis, and using low cost starting reagents. It can also be easily scaled from the bench to the manufacturing process.

Published: 11/18/2015 | Updated: 7/19/2013 | Inventor(s): Andre Beauchemin, Wei Gan, Christian Clavette, Tom Markiewicz, Amy Toderian

Keywords(s): Other

Category(s): Bio-Tech, Chemistry, Life Sciences, Manufacturing & Materials

Non-invasive 3D Imaging using CARS

Coherent anti-Stokes Raman scattering (CARS) is a powerful imaging technique that can be used for three dimensional imaging of molecules in live cells and tissue in a dynamic and non-invasive manner. It exhibits a 3D sectioning capability, high sensitivity, and high chemical specificity, which enables advanced studies of blood samples and other tissues...

Published: 5/1/2026 | Updated: 7/19/2013 | Inventor(s): Hanan Anis, Sangeeta Murugkar, Peter Stys

Keywords(s): E-Society, Health

Category(s): Bio-Tech, Chemistry, Engineering, Life Sciences

Real Time detection of molecules

This system uses enhanced Raman spectroscopy to analyze molecules for a real time analysis of compounds in the field or laboratory. The user takes a small sample, fills the modified micro-cuvette, and puts it into the portable analyzer to quantify the desired compound within minutes. This technology can be adapted to detect a variety of molecules for...

Published: 12/11/2019 | Updated: 7/19/2013 | Inventor(s): Hanan Anis, Majid Naji, Altaf Khetani

Keywords(s): E-Society, Health, Molecular and Environmental Sciences

Category(s): Life Sciences, Bio-Tech, Chemistry, Engineering, Manufacturing & Materials

Stable and Low cost Peptides; Improved Synthesis of Natural and Synthetic Amino Acids

This one step reaction to amino acids and their derivatives uses inexpensive starting material. It can be used for developing simple synthetic routes to inexpensive natural and synthetic proteins for pharmaceuticals, agrochemicals, and research needs. Synthetic derivatives retain activity, while protecting the peptides from damaging enzymes. Description:...

Published: 11/18/2015 | Updated: 7/3/2013 | Inventor(s): Andre Beauchemin, Christian Clavette, Jean-Francois Vincent-Rocan

Keywords(s): Health, Molecular and Environmental Sciences

Category(s): Chemistry, Life Sciences, Manufacturing & Materials, Sustainable Technology, Bio-Tech

An Improved PCR-Based Method for DNA Assembly

The improved PCR-based method for DNA assembly allows for the assembly of DNA molecules in the 4-10 kb range from monomers or dimers with improved efficiency and in a shorter time compared to the methods currently available in the field. The method allows for the assembled DNA molecule to be integrated directly into a plasmid (e.g. E. coli shuttle vector)...

Published: 6/19/2013 | Updated: 7/18/2012 | Inventor(s): Alexander Power, Mads Kaern, Daniel Jedrysiak

Keywords(s): Molecular and Environmental Sciences

Category(s): Bio-Tech, Life Sciences

Microfluidic Flow Cytometer - Lab on a chip cell sorting and analysis

This technology enables dynamic tuning of channels in chip based microfluidic devices. In a single PDMS chip, this technology enables improved sensitivity, and extended detection to a greater range of particles sizes than is typical of existing flow cytometers. The ability of the end user to adjust the size of the microchannels makes it possible for...

Published: 6/19/2013 | Updated: 5/16/2012 | Inventor(s): Michel Godin, Jason Riordon

Keywords(s): Molecular and Environmental Sciences, Other

Category(s): Bio-Tech, Life Sciences, Manufacturing & Materials

Compact and Low Cost Femtosecond Laser

This femtosecond laser is fiber based, providing the potential to greatly reduce e size and manufacturing costs of ultrashort laser sources. This will lead to new applications for femtosecond lasers such as confocal and nonlinear optical microscopy, dentistry (surgery and cosmetics), micro-machining, ophthalmology (laser eye surgery), and other surgical...

Published: 11/18/2015 | Updated: 5/16/2012 | Inventor(s): Hanan Anis, Mohammed Abdel Alim

Keywords(s): E-Society, Other

Category(s): Bio-Tech, Engineering, Life Sciences, Manufacturing & Materials

Anis/Murugkar - CARS Microscopy

Coher ent ant i-St okes Raman scat t er ing (CARS) is a nonlinear opt ical pr ocess r elat ed t o Raman scat t er ing CARS is a power f ul imaging t echnique f or biological samples t hat pr ovides high r esolut ion and chemical selectivity. To cr eate CARS signal, t wo specially t uned laser beams ar e used t o cr eat e a t hir d beat f r equency. When...

Published: 11/18/2015 | Updated: 2/3/2012 | Inventor(s): Sangeeta Murugkar, Hanan Anis, Xiaoliang Sunney Xie, Conor Evans

Keywords(s): Health, Other

Category(s): Bio-Tech